TUESDAY, Oct. 19, 2021 (HealthDay Information) — Whereas they’re serving to to ease reflux, some heartburn medication might also be lowering the severity of gum illness, new analysis suggests.
For the research, researchers assessed probing depth within the gums (the hole between tooth and gums) in additional than 1,000 sufferers with gum illness who have been or weren’t utilizing medication referred to as proton pump inhibitors (PPIs), a category of medication broadly prescribed to deal with heartburn, acid reflux disease and ulcers.
Probing depth is an indicator of gum illness (periodontitis) severity. When gums are wholesome, they match snugly in opposition to the tooth and there’s a smaller probing depth.
The decrease severity of gum illness related to PPIs could also be resulting from how the medication alter bone metabolism and the intestine microbiome, in accordance with lead investigator Dr. Lisa Yerke. She is a scientific assistant professor on the College at Buffalo Faculty of Dental Medication, in New York.
PPIs embrace medication like Prilosec (omeprazole) and Nexium (esomeprazole).
Probing depths of 6 millimeters (mm) or extra have been present in 14% of tooth in sufferers who used PPIs, in contrast with 24% of tooth from sufferers who didn’t use PPIs, the findings confirmed.
Probing depths of 5 mm or extra have been present in 27% of tooth in sufferers utilizing PPIs, in contrast with 40% of tooth from these not utilizing PPIs, the research authors reported.
The outcomes have been lately printed on-line within the journal Clinical and Experimental Dental Research.
“PPIs may doubtlessly be utilized in mixture with different periodontal therapies; nevertheless, further research are first wanted to grasp the underlying mechanisms behind the function PPIs play in lowering the severity of periodontitis,” Yerke mentioned in a college information launch.
The research can’t show a cause-and-effect relationship. Additional analysis is being deliberate to study whether or not this affiliation between PPIs and gum illness will be present in different teams of sufferers, and to find out how a lot of this relationship is immediately attributable to PPIs, Yerke mentioned.
The American Academy of Periodontology has extra on gum disease.
SOURCE: College at Buffalo, information launch, Oct. 18, 2021